
Air Europa's Lowest Priced Flights from Panama from 744 USD!
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Search Top Routes and Airfare Deals from PanamaÂ
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USD

Panama City (PTY)to
Madrid (MAD)04/08/2026 - 04/17/2026
From
928Â USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to
Barcelona (BCN)04/11/2026 - 04/19/2026
From
1.136Â USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to
Milan (MXP)04/13/2026 - 04/19/2026
From
1.073Â USD
Viewed 16 hours ago
Round trip
Economy

Panama City (PTY)to
Valencia (VLC)04/04/2026 - 04/14/2026
From
1.455Â USD
Viewed 21 hours ago
Round trip
Economy

Panama City (PTY)to
Bilbao (BIO)03/27/2026 - 04/11/2026
From
1.427Â USD
Viewed 47 minutes ago
Round trip
Economy

Panama City (PTY)to
Malaga (AGP)04/02/2026 - 04/14/2026
From
1.127Â USD
Viewed 23 hours ago
Round trip
Economy

Panama City (PTY)to
Brussels (BRU)04/09/2026 - 04/19/2026
From
1.139Â USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to
Zurich (ZRH)04/11/2026 - 05/15/2026
From
1.186Â USD
Viewed 16 hours ago
Round trip
Economy

Panama City (PTY)to
Porto (OPO)03/20/2026 - 03/24/2026
From
1.550Â USD
Viewed 9 hours ago
Round trip
Economy

Panama City (PTY)to
Alicante (ALC)03/27/2026 - 04/01/2026
From
1.393Â USD
Viewed 15 hours ago
Round trip
Economy

Panama City (PTY)to
Paris (CDG)04/10/2026 - 05/04/2026
From
2.225Â USD
Viewed 14 hours ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Search Top Routes and Airfare Deals from PanamaÂ
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From | To | Trip type | Dates | Price |
|---|---|---|---|---|
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 05/18/2026 - 05/26/2026 | From 744Â USD Viewed 57 minutes ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 05/19/2026 - 05/31/2026 | From 783Â USD Viewed 12 hours ago |
| Panama City (PTY) | Milan (MXP) | Round trip | Economy | 08/25/2026 - 09/05/2026 | From 1.011Â USD Viewed 19 hours ago |
| Panama City (PTY) | Valencia (VLC) | Round trip | Economy | 05/05/2026 - 05/10/2026 | From 862Â USD Viewed 11 hours ago |
| Panama City (PTY) | Bilbao (BIO) | Round trip | Economy | 06/09/2026 - 06/29/2026 | From 963Â USD Viewed 23 hours ago |
| Panama City (PTY) | London (LGW) | Round trip | Economy | 05/30/2026 - 06/15/2026 | From 1.102Â USD Viewed 20 hours ago |
| Panama City (PTY) | Malaga (AGP) | Round trip | Economy | 04/19/2026 - 05/06/2026 | From 991Â USD Viewed 2 hours ago |
| Panama City (PTY) | Frankfurt (FRA) | Round trip | Economy | 06/19/2026 - 09/15/2026 | From 921Â USD Viewed 2 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 05/14/2026 - 06/16/2026 | From 902Â USD Viewed 20 hours ago |
| Panama City (PTY) | Brussels (BRU) | Round trip | Economy | 05/19/2026 - 05/26/2026 | From 941Â USD Viewed 15 hours ago |
| Panama City (PTY) | Zurich (ZRH) | Round trip | Economy | 12/06/2026 - 12/13/2026 | From 974Â USD Viewed 21 hours ago |
| Panama City (PTY) | Amsterdam (AMS) | Round trip | Economy | 10/22/2026 - 11/01/2026 | From 878Â USD Viewed 2 hours ago |
| Panama City (PTY) | Porto (OPO) | Round trip | Economy | 07/01/2026 - 07/12/2026 | From 1.069Â USD Viewed 21 hours ago |
| Panama City (PTY) | Venice (VCE) | Round trip | Economy | 05/30/2026 - 06/13/2026 | From 943Â USD Viewed 16 hours ago |
| Panama City (PTY) | Lisbon (LIS) | Round trip | Economy | 06/10/2026 - 09/08/2026 | From 843Â USD Viewed 14 hours ago |
| Panama City (PTY) | Istanbul (IST) | Round trip | Economy | 10/07/2026 - 10/21/2026 | From 1.076Â USD Viewed 20 hours ago |
| Panama City (PTY) | Alicante (ALC) | Round trip | Economy | 03/27/2026 - 04/01/2026 | From 1.393Â USD Viewed 15 hours ago |
| Panama City (PTY) | Palma de Mallorca (PMI) | Round trip | Economy | 05/25/2026 - 05/31/2026 | From 1.025Â USD Viewed 5 hours ago |
| Panama City (PTY) | Tenerife (TFN) | Round trip | Economy | 05/01/2026 - 05/10/2026 | From 1.039Â USD Viewed 19 hours ago |
| Panama City (PTY) | Athens (ATH) | Round trip | Economy | 07/01/2026 - 07/13/2026 | From 1.082Â USD Viewed 3 hours ago |
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Departing from Panama
Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.
Flights from Panama with Air Europa
Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.
- If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
- Visit the currency exchange and ATM.
- Find last-minute souvenirs at the duty-free shops.
- Replenish your toiletries and medications at the pharmacy.
Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.
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| Route | Basic Economy Price<br /><span style="font-size: 7pt;">*Each way based on roundtrip purchase</span> | Standard Economy Price<br /><span style="font-size: 7pt;">*Each way based on roundtrip purchase</span> |
|---|---|---|
From Denver (DEN) To Lubbock (LBB) | $59 | $89 |
From Houston (IAH) To Corpus Christi (CRP) | $59 | $89 |
From Los Angeles (LAX) To Sacramento (SMF) | $59 | $89 |
From Chicago (ORD) To Cincinnati (CVG) | $59 | $89 |
From Chicago (ORD) To Dayton (DAY) | $59 | $89 |
From Washington, D.C. (IAD) To Dayton (DAY) | $74 | $104 |
From San Francisco (SFO) To Phoenix (PHX) | $77 | $107 |
From Denver (DEN) To Kansas City (MCI) | $79 | $109 |
From Denver (DEN) To Omaha (OMA) | $81 | $111 |
From Chicago (ORD) To Detroit (DTW) | $83 | $113 |
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