
Air Europa's Lowest Priced Flights from Panama from 742 USD!
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Search Top Routes and Airfare Deals from PanamaÂ
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USD

Panama City (PTY)to
Madrid (MAD)08/04/2026 - 19/04/2026
From
929Â USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to
Barcelona (BCN)15/04/2026 - 29/04/2026
From
1.224Â USD
Viewed 17 hours ago
Round trip
Economy

Panama City (PTY)to
Milan (MXP)31/03/2026 - 12/04/2026
From
1.297Â USD
Viewed 23 hours ago
Round trip
Economy

Panama City (PTY)to
Bilbao (BIO)16/04/2026 - 01/05/2026
From
1.031Â USD
Viewed 21 hours ago
Round trip
Economy

Panama City (PTY)to
London (LGW)26/03/2026 - 29/03/2026
From
2.009Â USD
Viewed 40 minutes ago
Round trip
Economy

Panama City (PTY)to
Frankfurt (FRA)25/03/2026 - 28/03/2026
From
1.930Â USD
Viewed 4 hours ago
Round trip
Economy

Panama City (PTY)to
Paris (ORY)03/04/2026 - 25/07/2026
From
1.835Â USD
Viewed 30 minutes ago
Round trip
Economy

Panama City (PTY)to
Brussels (BRU)08/04/2026 - 21/04/2026
From
1.138Â USD
Viewed 33 minutes ago
Round trip
Economy

Panama City (PTY)to
Zurich (ZRH)15/04/2026 - 03/05/2026
From
1.139Â USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to
Porto (OPO)16/04/2026 - 27/04/2026
From
1.074Â USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to
Vigo (VGO)13/04/2026 - 13/10/2026
From
1.160Â USD
Viewed 20 hours ago
Round trip
Economy

Panama City (PTY)to
Lisbon (LIS)15/04/2026 - 30/04/2026
From
1.177Â USD
Viewed 18 hours ago
Round trip
Economy

Panama City (PTY)to
Lanzarote (ACE)20/03/2026 - 02/08/2026
From
2.007Â USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to
Paris (CDG)08/04/2026 - 15/04/2026
From
2.129Â USD
Viewed 22 hours ago
Round trip
Economy

Panama City (PTY)to
Munich (MUC)10/04/2026 - 25/04/2026
From
2.025Â USD
Viewed 6 hours ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Search Top Routes and Airfare Deals from PanamaÂ
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USD
From | To | Trip type | Dates | Price |
|---|---|---|---|---|
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 24/05/2026 - 31/05/2026 | From 742Â USD Viewed 3 hours ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 19/05/2026 - 04/06/2026 | From 797Â USD Viewed 23 hours ago |
| Panama City (PTY) | Milan (MXP) | Round trip | Economy | 07/05/2026 - 13/05/2026 | From 884Â USD Viewed 15 hours ago |
| Panama City (PTY) | Valencia (VLC) | Round trip | Economy | 10/08/2026 - 01/09/2026 | From 939Â USD Viewed 16 hours ago |
| Panama City (PTY) | Bilbao (BIO) | Round trip | Economy | 07/05/2026 - 18/05/2026 | From 864Â USD Viewed 22 hours ago |
| Panama City (PTY) | London (LGW) | Round trip | Economy | 03/07/2026 - 15/08/2026 | From 1.099Â USD Viewed 3 minutes ago |
| Panama City (PTY) | Malaga (AGP) | Round trip | Economy | 08/06/2026 - 24/06/2026 | From 820Â USD Viewed 1 hour ago |
| Panama City (PTY) | Frankfurt (FRA) | Round trip | Economy | 17/05/2026 - 22/05/2026 | From 925Â USD Viewed 4 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 30/09/2026 - 30/11/2026 | From 902Â USD Viewed 4 hours ago |
| Panama City (PTY) | Brussels (BRU) | Round trip | Economy | 08/04/2026 - 21/04/2026 | From 1.138Â USD Viewed 33 minutes ago |
| Panama City (PTY) | Zurich (ZRH) | Round trip | Economy | 05/06/2026 - 14/06/2026 | From 973Â USD Viewed 2 hours ago |
| Panama City (PTY) | Amsterdam (AMS) | Round trip | Economy | 05/11/2026 - 15/11/2026 | From 878Â USD Viewed 22 hours ago |
| Panama City (PTY) | Porto (OPO) | Round trip | Economy | 30/10/2026 - 12/11/2026 | From 937Â USD Viewed 17 hours ago |
| Panama City (PTY) | Tel Aviv (TLV) | Round trip | Economy | 01/05/2026 - 17/05/2026 | From 1.153Â USD Viewed 23 hours ago |
| Panama City (PTY) | Venice (VCE) | Round trip | Economy | 01/06/2026 - 07/06/2026 | From 875Â USD Viewed 22 hours ago |
| Panama City (PTY) | Vigo (VGO) | Round trip | Economy | 19/05/2026 - 25/05/2026 | From 758Â USD Viewed 22 hours ago |
| Panama City (PTY) | Lisbon (LIS) | Round trip | Economy | 15/04/2026 - 30/04/2026 | From 1.177Â USD Viewed 18 hours ago |
| Panama City (PTY) | Alicante (ALC) | Round trip | Economy | 31/05/2026 - 12/06/2026 | From 788Â USD Viewed 21 hours ago |
| Panama City (PTY) | Palma de Mallorca (PMI) | Round trip | Economy | 19/04/2026 - 27/04/2026 | From 1.046Â USD Viewed 1 hour ago |
| Panama City (PTY) | Lanzarote (ACE) | Round trip | Economy | 20/03/2026 - 02/08/2026 | From 2.007Â USD Viewed 2 hours ago |
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Departing from Panama
Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.
Flights from Panama with Air Europa
Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.
- If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
- Visit the currency exchange and ATM.
- Find last-minute souvenirs at the duty-free shops.
- Replenish your toiletries and medications at the pharmacy.
Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.
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| Route | Basic Economy Price<br /><span style="font-size: 7pt;">*Each way based on roundtrip purchase</span> | Standard Economy Price<br /><span style="font-size: 7pt;">*Each way based on roundtrip purchase</span> |
|---|---|---|
From Denver (DEN) To Lubbock (LBB) | $59 | $89 |
From Houston (IAH) To Corpus Christi (CRP) | $59 | $89 |
From Los Angeles (LAX) To Sacramento (SMF) | $59 | $89 |
From Chicago (ORD) To Cincinnati (CVG) | $59 | $89 |
From Chicago (ORD) To Dayton (DAY) | $59 | $89 |
From Washington, D.C. (IAD) To Dayton (DAY) | $74 | $104 |
From San Francisco (SFO) To Phoenix (PHX) | $77 | $107 |
From Denver (DEN) To Kansas City (MCI) | $79 | $109 |
From Denver (DEN) To Omaha (OMA) | $81 | $111 |
From Chicago (ORD) To Detroit (DTW) | $83 | $113 |
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